Hmmmmmm. Well probably B2B, that was so special, in spite of being port intensive. The weather, food, LCT'ers, it was magical.
Our other favorites would be a tie between CROSS and WINE - which was our very first trip to Europe.
As to worst, can't really say, we have had some that we said we wouldn't do again, but as Frank always says "I've never met a cruise I didn't like, I just like some better than others".