Hi Pam
We have spent lots of time in Prague and got married there in 2005. It is a wonderful place.
We have never had a guide, so can't help you there but it is a great city to just wander round. Don't miss the castle (Hradcany) including Golden lane with shops in all the old houses and the changing of the guards.
There are some fabulous bars and restaurants - and fantastic dining for a fraction of the price it would be here.
This is a great website
http://www.inyourpocket.com/cr/prague/en/ If you want to know specifics then please feel free to ask