Wow, good for you, Anne! You two sure do travel alot.
Yes, I've never been to Wales, so very interested. Are you going to be doing any hiking?
It's a long way out right now, but I'm thinking, drop the cruise stuff at Heathrow luggage storage, then pop on a train to somewhere like Oxford, then maybe Shrewsbury, and on to Wales. Or, Oxford then the Cotswalds and Devon/Cornwall. Done the latter a bit, but we both really loved that part of the country. David's never done Oxford, but I spent a week there a few years back, and he *must* go there.
Car or train, not sure--maybe do one of the combo passes, a bit of both.
Enjoy your trip!