Wendy, Regent very clear on this once you get closer to sailing or perhaps there is a notation when you call up the cruise on their website. I posted my experience because I seem to remember several years ago on CC Neviboy did not want to get the shot and found a way that he didn't have to. Perhaps he can add more, but today's news is that it is required, by Regent. Not a big deal for me, but it was not offered by my county health department, as it is in some areas more populated than mine.