Don,
We did a 3 day from Vancouver to Los Angeles this past Sept. (on Princess - Island Princess) with no port stops. I read so many posts before we booked that going from Los Angeles to Vancouver almost always had rough seas compared to the relatively calm reverse itinerary of Vancouver to Los Angeles. We found our seas to be quite calm, as everyone said it would be. Moral of this story - listen to as many opinions as you can find about East vs West and vice versa. Then take a consensus and make your decision. Based on the answers here so far from Margo, Marc & Michele it looks like East vs West is winning.
Sounds like fun!!!! Maybe you can organize a Mystery Dinner while on board. That will keep you busy!!!